Antidiabetic Effects of IGFBP2, a Leptin-Regulated Gene
Cell Metabolism - 6 January 2010 (Vol. 11, Issue 1, pp. 11-22) -Kristina Kedbacker, Kivanc Birsoy, Robert W. Wysocki, Esra Asilmaz, Rexford S. Ahima, I. Sadaf Farooqi, Jeffrey M. Friedman
Research study that shows that Leptin has been shown to improve hyperglycemia and insulin resistance in a number of clinical settings in animals and humans.
We would like to point out the fact that this research is still in the early stages with regards to human subjects and "further studies will reveal whether IGFBP2 shows similar antidiabetic effects in clinical settings."